Various Citrus

Diosmin+Hesperdin 90:10

CAS No.: 520-33-2/520-26-3

Specification: Micronized, DC

Product Source: Citrus Aurantium L.

It is the mixture of Diosmin and Hesperidin, which is widely used for pharmaceutical and food supplement.

Description

 

1.Diosmin is a semisynthetic flavonoid molecule derived from citrus d (modified hesperidin).

The product is used for treating various disorders of blood vessels including hemorrhoids, varicose veins, poor circulation in the legs (venous stasis), and bleeding (hemorrhage) in the eye or gums.

2.Hesperidin is a flavonoid found in the rinds of citrus fruits (such as oranges, lemons or pumelo fruits). The peel and membranous parts of these fruits have the highest hesperidin concentrations, especially in immature little citrus fruits. It is one of the flavonoids that give citrus fruits their color and taste.

Diosmin+Hesperdin 90:10​

SPECIFICATION SHEET

Product NameDiosmin+Hesperidin (90/10)
Botanical SourceCitrus Aurantium L.
Used PartImmature fruit
CodeBPBE-612-A
SpecificationDiosmin≥81.0%, Hesperidin≥8.0%
AppearanceGreyish-yellow or light yellow, hygroscopic powder
SolubilityPractically insoluble in water, soluble in dimethyl sulfoxide, practically insoluble in ethanol (96%), it dissolves in dilute solution of alkali hydroxides
Particle SizeNLT 95% pass 80 mesh
Water≤6.0%
Sulphated Ash≤0.2%
Heavy Metals≤20ppm
Iodine Content≤0.1%
Related Substances 
Impurity A(Acetoisovanillone)≤0.5%
Impurity C(Isorhoifolin)≤3.0%
Impurity D(6-iododiosmin)≤0.6%
Impurity E(Linarin)≤3.0%
Impurity F(Diosmetin)≤2.0%
Unspecified Impurities(each)≤0.4%
Total Impurities≤6.0%
AssayDiosmin≥81.0; Hesperidin≥8.0%
Residual Solvents 
Methanol≤3000ppm
Ethanol≤5000ppm
Pyridine≤200ppm
Total Plate Count≤1000cfu/g
Yeast & Mold≤100cfu/g
E.ColiNegative
SalmonellaNegative
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